This is what MT-CONNECT and MedTech Summit 2018 have to offer.
N2B-patch - Formulations for intranasal delivery of drugs
As a project coordinator, the Fraunhofer IGB is involved in the development of a medical therapy for the administration of active ingredients via the olfactoria region within the EU-funded project »N2B-patch«. Within the project, the Fraunhofer IGB focuses on the formulation of the particles containing the active substance and the embedding of these particles into hydrogels.
A key factor in the development of functional ingredients or active substances is their transport to their target location. The Fraunhofer IGB is working on particle-based formulations for the transport of these substances to the site of action in a targeted manner (drug delivery) and to deliver them in a controlled manner (drug release). Medically active substances are normally distributed via the blood – either directly by injection into the bloodstream or indirectly, for example through the digestive tract after oral administration. In many diseases, however – for example of the central nervous system – it is of decisive importance to transport the active substance as efficiently as possible to the required target site. An example of this is the treatment of multiple sclerosis, where the pharmaceutical agents have to produce their effect above all in the central nervous system. However, this is especially difficult to achieve in the usual way via the blood due to special protective mechanisms such as the blood-brain barrier. Within the scope of the EU-funded “N2B patch” cooperative project, Fraunhofer IGB is therefore participating in the development of a medical form of therapy that delivers the drug via the Regio olfactoria. The therapeutic system will consist of the active agent itself, of a formulation containing the active agent, a hydrogel as carrier material for the formulation, and a suitable applicator. In the project the Fraunhofer IGB is concentrating on the formulation of the particles containing the active agent, and on inserting these particles into hydrogels.
--- Date: 12.04.2018 Time: 1:25 PM - 1:50 PM Location: Hall Brüssel II, NCC Mitte